The ULP has proven itself in recent years as a safe partner for conducting practice-related research due to the large number of dairy and pig farms in our practice, the availability of data and the collaboration with the Faculty of Veterinary Medicine. We are ISO-9001 certified and have our ow laboratory (Click HERE for more information about our laboratory). This makes the ULP the partner you are looking for to conduct reasearch such as clinical studies and registry  studies, prevelance studies, welfare studies an surveys.

The experienced research team consists of veterinarians with a doctorate, European specialists (dipl. ECBHM and dipl. ECPHM) and specialists in training. In addition, the ULP has an experienced research assistant who is responsible for practical implementation and data management.

In the field of research, the ULP offers you:

  • Extensive expertise in the health care of (small) ruminants and pigs
  • High caseload due to a large number of present animals
  • Great variation in different types of companies
  • Expertise in making a study design
  • Extensive experience in the implementation and analysis of randomized clinical trials.

Since the founding of the ULP in 2009, a large number of studies have been carried out. Below you wil find the details of two studies and a overview of the studies that have been carried out. Most studies resulted in a scientific publication in a peer-reviewed paper or presentation at scientific congresses.

If you have any questions about the research possibilities we could offer or would you like to use our expertise in setting up a field study, then please contact us.


The following scientific publications have appeared from the various studies that we have conducted over the years:

Use of paracetamol in sows around farrowing: effect on health and condition of the sow, piglet mortality, piglet weight and piglet weight gain. Wikke Kuller, Steven Sietsma, Susan Hendriksen & Daniel Sperling  Porcine Health Management volume 7, Article number: 46. 2021

M-score and wound healing assessment of two nonantibiotic topical gel treatments of active digital dermatitis lesions in dairy cattle. Vanhoudt A, Hesseling J, Nielen M, Wilmink J, Jorritsma R, van Werven T. J Dairy Sci. 2021 Oct 8:S0022-0302(21)00942-5. doi: 10.3168/jds.2021-20613.

Reproductive hormone use and its association with herd-level factors on Dutch dairy farms. van der Laan JSM, Vos PLAM, van den Borne BHP, Aardema H, van Werven T. J Dairy Sci. 2021 Dry period management and new high somatic cell count during the dry period in Dutch dairy herds under selective dry cow therapy.

Dry period management and new high somatic cell count during the dry period in Dutch dairy herds under selective dry cow therapy. Krattley-Roodenburg B, Huybens LJ, Nielen M, van Werven T. J Dairy Sci. 2021 Jun;104(6):6975-6984. doi: 10.3168/jds.2020-19133.Oct;104(10):10854-10862. doi: 10.3168/jds.2020-19786.

Bacterial flora associated with udder cleft dermatitis in Dutch dairy cows. van Engelen E, Dijkstra T, Meertens NM, van Werven T. J Dairy Sci. 2021 Jan;104(1):728-735. doi: 10.3168/jds.2020-18414.

Incidence of milk leakage after dry-off in European dairy herds, related risk factors and its role in new intramammary infections. J Dairy Sci 2020 de Prado-Taranilla, Ana, Holstege, Manon  Bertocchi, Appiani, Becvar, Davidek, Jiri , Nielsen, Dorte, Jimenez, Luisme, Roger, Nuria Krömker, Volker , Paduch, Jan- Piepers, Sofie, Wuytack, Ameline, Veenkamp, Annemiek, van Werven, Dalez, BrunoLe Page, Phillippe Schukken, Velthuis, Annet.

Antimicrobial use and farmers’ attitude toward mastitis treatment on dairy farms with automatic or conventional milking systems. Deng Z, Lam TJGM, Hogeveen H, Spaninks M, Heij N, Postema M, van Werven T, Koop G. J Dairy Sci. 2020 May 28:S0022-0302(20)30409-4. doi: 10.3168/jds.2019-17960

Interobserver agreement of digital dermatitis M-scores for photographs of the hind feet of standing dairy cattle. Vanhoudt A, Yang DA, Armstrong T, Huxley JN, Laven RA, Manning AD, Newsome RF, Nielen M, van Werven T, Bell NJ. J Dairy Sci. 2019 Jun;102(6):5466-5474. doi: 10.3168/jds.2018-15644. Epub 2019 Apr 4.

Longitudinal study of udder cleft dermatitis in five Dutch dairy cattle herds. A. Bouma, M. Nielen, E. van Soest, S. Sietsma, J. van den Broek, T. Dijkstra, and T. van Werven. J Dairy Sci. 2016 Jun; 99(6):4487-95

Pan-European agreement on dry cow therapy. Bradley A, De Vliegher S, Farre M, Jimenez LM, Peters T, de Leemput ES, van Werven T. Vet Rec. 2018 Jun 2;182(22):637. doi: 10.1136/vr.k2382.

High Production of LukMF’ in Staphylococcus aureus Field Strains Is Associated with Clinical Bovine Mastitis. Hoekstra J, Rutten V, Sommeling L, van Werven T, Spaninks M, Duim B, Benedictus L, Koop G. Toxins (Basel). 2018 May 15;10(5):200. doi: 10.3390/toxins10050200.

Effects of reduced intramammary antimicrobial use during the dry period on udder health in Dutch dairy herds. Vanhoudt A, van Hees-Huijps K, van Knegsel ATM, Sampimon OC, Vernooij JCM, Nielen M, van Werven T. J Dairy Sci. 2018 Apr;101(4):3248-3260. doi: 10.3168/jds.2017-13555. Epub 2018 Feb 1.

A randomized clinical trial of topical treatments for mild and severe udder cleft dermatitis in Dutch dairy cows. van Werven T, Wilmink J, Sietsma S, van den Broek J, Nielen M. J Dairy Sci. 2018 Sep;101(9):8259-8268. doi: 10.3168/jds.2017-13778. Epub 2018 Jul 4.

Dynamics of faecal shedding of ESBL- or AmpC-producing Escherichia coli on dairy farms. Hordijk J, Fischer EAJ, van Werven T, Sietsma S, Van Gompel L, Timmerman AJ, Spaninks MP, Heederik DJJ, Nielen M, Wagenaar JA, Stegeman A. J Antimicrob Chemother. 2019 Jun 1;74(6):1531-1538. doi: 10.1093/jac/dkz035.

Addition of meloxicam to the treatment of clinical mastitis improves subsequent reproductive performance. S. McDougall, E. Abbeloos, S. Piepers, A.S. Rao, S. Astiz,T. van Werven, J. Statham, and N. Pérez- Villalobos. J Dairy Sci. 2016 Mar; 99(3):2026-42

An investigation of the dynamics of intramammary infections acquired during the dry period on European dairy farms. Bradley AJ, De Vliegher S, Green MJ, Larrosa P, Payne B, van de Leemput ES, Samson O, Valckenier D, Van Werven T, Waldeck HW, White V, Goby L. J Dairy Sci. 2015 Sep;98(9):6029-47.

Short communication: Protease activity measurement in milk as a diagnostic test for clinical mastitis in dairy cows. Koop G, van Werven T, Roffel S., Hoogeveen H., Nazmi K., Bikker FJ. J Dairy Sci. 2015 Jul;98(7):4613-8.

Comparison of two intravaginal progesterone releasing devices (PRID vs CIDR) in diary cows: blood pr0gesterone profile and field fertility. van Werven T, Waldeck F, Souza A, Floch S, Englebienne M. Anim Reprod Sci. 2013 May;138(3-4):143-9